As far as I noticed There are three moments when there is smoke, after the car accident, after the suicide and when Joe shoots the vacuüm cleaner after the mess up with te thee killings. Is smoke important and the number 3? 3 appartments 3 Winky's, And so on.

And in club silencio I believe?

U are absolutely right but is there a meaning to it like the sleeping/dreaming/waking up, coffee cups, red clothing, phones ringing and so on?